| Publications | |||
|---|---|---|---|
| 2018 | MAP3K1 and MAP2K4 mutations are associated with favorable response to MEK inhibitors in multiple cancer models Cell Research 2018, 28 pp719-729, doi:10.1038/s41422-018-0044-4 [Link to Article] | Zheng Xue, Daniel J. Vis, Alejandra Bruna, Tonci Sustic, Sake van Wageningen, Ankita Sati Batra, Oscar M. Rueda, Evert Bosdriesz, Carlos Caldas, Lodewyk F. A. Wessels and René Bernards | |
| 2017 | DNA repair deficiency biomarkers and the 70-gene ultra-high risk signature as predictors of veliparib/carboplatin response in the I-SPY 2 breast cancer trial NPJ Breast Cancer 2017, 3(31), doi:10.1038/s41523-017-0025-7 [Link to Article] | Denise M. Wolf, Christina Yau, Ashish Sanil, Annuska Glas, Emanuel Petricoin, Julia Wulfkuhle, Tesa M. Severson, Sabine Linn, Lamorna Brown-Swigart, Gillian Hirst, Meredith Buxton, Angela DeMichele, Nola Hylton, Fraser Symmans, Doug Yee, Melissa Paoloni, Laura Esserman, Don Berry, Hope Rugo, Olufunmilayo Olopade and Laura van ‘t Veer | |
| 2017 | Master Transcriptional Regulators in Cancer: Discovery via Reverse Engineering Approaches and Subsequent Validation Cancer Research 2017, 77(9) pp2186-2190, doi:10.1158/0008-5472.CAN-16-1813 [Link to Article] |
Bruce Moran, Arman Rahman, Katja Palonen, Fiona T. Lanigan and William M. Gallagher | |
| 2017 | The BRCA1ness signature is associated significantly with response to PARP inhibitor treatment versus control in the I-SPY 2 randomized neoadjuvant setting Breast Cancer Research 2017, 19(1):99, doi:10.1186/s13058-017-0861-2 [Link to Article] |
Severson TM, Wolf DM, Yau C, Peeters J, Wehkam D, Schouten PC, Chin SF, Majewski IJ, Michaut M, Bosma A, Pereira B, Bismeijer T, Wessels L, Caldas C, Bernards R, Simon IM, Glas AM, Linn S, van ‘t Veer L. | |
| 2017 | High Estrogen Receptor β Expression Is Prognostic among Adjuvant Chemotherapy–Treated Patients—Results from a Population-Based Breast Cancer Cohort Clinical Cancer Research 2017, 23(3) pp766-777, doi:10.1158/1078-0432.CCR-16-1095 [Link to Article] |
Karin Elebro, Signe Borgquist, Ann H. Rosendahl, Andrea Markkula, Maria Simonsson, Karin Jirström, Carsten Rose, Christian Ingvar and Helena Jernström | |
| 2017 | Combined and individual tumor-specific expression of insulin-like growth factor-I receptor, insulin receptor and phospho-insulin-like growth factor-I receptor/insulin receptor in primary breast cancer: Implications for prognosis in different treatment groups Oncotarget 2017, 8(6) pp 9093-9107, doi:10.18632/oncotarget.14082 [Link to Article] |
Björner S*, Rosendahl AH*, Simonsson M, Markkula A, Jirström K, Borgquist S, Rose C, Ingvar C, Jernström H. | |
| 2017 | The prognostic impact of COX-2 expression in breast cancer depends on oral contraceptive history, preoperative NSAID use, and tumor size International Journal of Cancer 2017, 140(1) 163-175, doi:10.1002/ijc.30432 [Link to Article] |
Simonsson M, Björner S, Markkula A, Nodin B, Jirström K, Rose C, Borgquist S, Ingvar C, Jernström H. | |
| 2017 | Therapeutic Rationale to Target Highly Expressed CDK7 Conferring Poor Outcomes in Triple-Negative Breast Cancer Cancer Research 2017, 77:14 doi:10.1158/0008-5472.CAN-16-2546 [Link to Article] |
Bo Li, Triona Ni Chonghaile, Yue Fan, Stephen F. Madden, Rut Klinger, Aisling E. O’Connor, Louise Walsh, Gillian O’Hurley, Girish Mallya Udupi, Jesuchristopher Joseph, Finbarr Tarrant, Emer Conroy, Alexander Gaber, Suet-Feung Chin, Helen A. Bardwell, Elena Provenzano, John Crown, Thierry Dubois, Sabine Linn, Karin Jirstrom, Carlos Caldas, Darran P. O’Connor and William M. Gallagher | |
| 2016 | Integration of genomic, transcriptomic and proteomic data identifies two biologically distinct subtypes of invasive lobular breast cancer Scientific Reports 2016, 6:18517, doi:10.1038/srep18517 [Link to Article] |
Magali Michaut, Suet-Feung Chin, Ian Majewski, Tesa M. Severson, Tycho Bismeijer, Leanne de Koning, Justine K. Peeters, Philip C. Schouten, Oscar M. Rueda, Astrid J. Bosma, Finbarr Tarrant, Yue Fan, Beilei He, Zheng Xue, Lorenza Mittempergher, Roelof J.C. Kluin, Jeroen Heijmans, Mireille Snel, Bernard Pereira, Andreas Schlicker, Elena Provenzano, Hamid Raza Ali, Alexander Gaber, Gillian O’Hurley, Sophie Lehn, Jettie J.F. Muris, Jelle Wesseling, Elaine Kay, Stephen John Sammut, Helen A. Bardwell, Aurélie S. Barbet, Floriane Bard, Caroline Lecerf, Darran P. O’Connor, Daniël J. Vis, Cyril H. Benes, Ultan McDermott, Mathew J. Garnett, Iris M. Simon, Karin Jirström, Thierry Dubois, Sabine C. Linn, William M. Gallagher, Lodewyk F.A. Wessels, Carlos Caldas & Rene Bernards | |
| 2015 | Tumor-specific expression of HMG-CoA reductase in a population-based cohort of breast cancer patients BMC Clinical Pathology, 2015, 15:8, doi:10.1186/s12907-015-0008-2 [Link to Article] |
Emma Gustbée, Helga Tryggvadottir, Andrea Markkula, Maria Simonsson, Björn Nodin, Karin Jirström, Carsten Rose, Christian Ingvar, Signe Borgquist and Helena Jernström | |
| 2015 | Robust BRCA1-like classification of copy number profiles of samples repeated across different datasets and platforms Molecular Oncology, 2015, 9(7):1274-1286, doi:10.1016/j.molonc.2015.03.002 [Link to Article] |
Philip C. Schouten, Anita Grigoriadis, Thomas Kuilman, Hasan Mirza, Johnathan A. Watkins, Saskia A. Cooke, Ewald van Dyk, Tesa M. Severson, Oscar M. Rueda, Marlous Hoogstraat, Caroline V.M. Verhagen, Rachael Natrajan, Suet-Feung Chin, Esther H. Lips, Janneke Kruizinga, Arno Velds, Marja Nieuwland, Ron M. Kerkhoven, Oscar Krijgsman, Conchita Vens, Daniel Peeper, Petra M. Nederlof, Carlos Caldas, Andrew N. Tutt, Lodewyk F. Wessels, Sabine C. Linn | |
| 2015 | Combined androgen and estrogen receptor status in breast cancer: treatment prediction and prognosis in a population-based prospective cohort Clinical Cancer Research, 2015, doi:10.1158/1078-0432.CCR-14-2564 [Link to Article] |
Karin Elebro, Signe Borgquist, Maria Simonsson, Andrea Markkula, Karin Jirström, Christian Ingvar, Carsten Rose, Helena Jernström | |
| 2015 | Delineating transcriptional networks of prognostic gene signatures refines treatment recommendations for lymph node-negative breast cancer patients FEBS Journal, 2015, doi:10.1111/febs.13354 [Link to Article] |
Fiona Lanigan, Gerard L. Brien, Yue Fan, Stephen F. Madden, Emilia Jerman, Fatima Aloraifi, Karsten Hokamp, Eiseart J. Dunne, Amanda J. Lohan, Louise Flanagan, James C. Garbe, Martha R. Stampfer, Marie Fridberg, Karin Jirström, Cecily M. Quinn, Brendan Loftus, William M. Gallagher, James Geraghty, Adrian P. Bracken | |
| 2015 | BRCA1-like signature in triple negative breast cancer: Molecular and clinical characterization reveals subgroups with therapeutic potential Molecular Oncology, 2015, doi:10.1016/j.molonc.2015.04.011 [Link to Article] |
Tesa M. Severson, Justine Peeters, Ian Majewski, Magali Michaut, Astrid Bosma, Philip C. Schouten, Suet-Feung Chin, Bernard Pereira, Mae A. Goldgraben, Tycho Bismeijer, Roelof J.C. Kluin, Jettie J.F. Muris, Karin Jirström, Ron M. Kerkhoven, Lodewyk Wessels, Carlos Caldas, René Bernards, Iris M. Simon, Sabine Linn | |
| 2015 | Epidemiologic Design and Analysis for Proteomic Studies: A Primer on -Omic Technologies American Journal of Epidemiology, 2015, 181(9):635-647, doi:10.1093/aje/kwu462 [Link to Article] |
Harald Mischak, Elena Critselis, Samir Hanash, William M. Gallagher, Antonia Vlahou, John P.A. Ioannidis | |
| 2015 | PIK3CA mutations are associated with decreased benefit to neoadjuvant human epidermal growth factor receptor 2- targeted therapies in breast cancer Journal of Clinical Oncology, 2015, 33(12):1334-1339, doi:10.1200/JCO.2014.55.2158 [Link to Article] |
Ian J. Majewski, Paolo Nuciforo, Lorenza Mittempergher, Astrid J. Bosma, Holger Eidtmann, Eileen Holmes, Christos Sotiriou, Debora Fumagalli, Jose Jimenez, Claudia Aura, Ludmila Prudkin, Maria Carmen Díaz-Delgado, Lorena de la Peña, Sherene Loi, Catherine Ellis, Nikolaus Schultz, Evandro de Azambuja, Nadia Harbeck, Martine Piccart-Gebhart, René Bernards and José Baselga | |
| 2014 | Impact of COX2 genotype, ER status and body constitution on risk of early events in different treatment groups of breast cancer patients International Journal of Cancer, 2014, 135:1989-1910, doi:10.1002/ijc.28831 [Link to Article] |
Andrea Markkula, Maria Simonsson, Ann H. Rosendahl, Alexander Gaber, Christian Ingvar, Carsten Rose and Helena Jernström | |
| 2014 | Development of a BRCA1-like signature in Triple Negative breast cancers within the RATHER (Rational Therapy for Breast Cancer) consortium Annals of Oncology, 2014, 25(suppl 1):i8. doi:10.1093/annonc/mdu066.3 [Link to Article] |
I.M. Simon, J. Peeters, T. Severson, I. Majewski, A. Bosma, C. Caldas, S. Chin, R. Bernards, S. Linn | |
| 2014 | Garbage in, Garbage out: A Critical Evaluation of Strategies Used for Validation of Immunohistochemical Biomarkers Molecular Oncology , 2014, 8(4):783-798, doi:10.1016/j.molonc.2014.03.008 [Link to Article] |
Gillian O’Hurley, Evelina Sjöstedt, Arman Rahman, Bo Li, Caroline Kampf, Fredrik Pontén, William M. Gallagher, Cecilia Lindskog | |
| 2013 | Investigation of Molecular Alterations of AKT-3 in Triple Negative Breast Cancer Histopathology, 2013 Oct 19 doi:10.1111/his.12313 [Link to Article] |
Gillian O’Hurley, Etáin Daly, Anthony O’Grady, Robert Cummins, Cecily Quinn, Louise Flanagan, Aisling Pierce, Yue Fan, Miriam A. Lynn, Máirín Rafferty, Dara Fitzgerald, Fredrik Pontén, Michael J. Duffy, Karin Jirström, Elaine W. Kay, William M. Gallagher | |
| 2013 | Correlating transcriptional networks to breast cancer survival: a large-scale coexpression analysis Carcinogenesis, 2013, 34(10):2300-2308, doi:10.1093/carcin/bgt208 [Link to Article] |
Colin Clarke, Stephen F. Madden, Padraig Doolan, Sinead T. Aherne, Helena Joyce, Lorraine O’Driscoll, William M. Gallagher, Bryan T. Hennessy, Michael Moriarty, John Crown, Susan Kennedy, Martin Clynes | |
| 2013 | BreastMark: an integrated approach to mining publicly available transcriptomic datasets relating to breast cancer outcome Breast Cancer Res. 2013 Jul 2;15(4):R52, doi:10.1186/bcr3444 [Link to Article] |
Stephen F. Madden, Colin Clarke, Sinead T. Aherne, Patricia Gaule, Norma O’Donovan, John Crown, Martin Clynes, William M. Gallagher | |
| 2013 | Biomarkers in drug discovery and development Book chapter, Encyclopedia of Pharmaceutical Science and Technology, 4th edition, Informa Healthcare, doi:10.1081/E-EPT4-120050197 [Link to Article] |
Miriam A Lynn, Gillian O’Hurley, Adrian Coyle, Balazs Balint, Marina Alamanou, William M. Gallagher | |
| Conferences | ||
|---|---|---|
| 2018 | Poster: Proteomic classification of Triple Negative Breast Cancers EACR Annual Meeting 2018, Amsterdam, The Netherlands, 30th June – 3rd July 2018 | Martina Sundqvist, Leanne de Koning, Guillem Rigaill, Thierry Dubois, Julien Chiquet |
| 2018 | Poster: Cluster stability for more robust classification in Triple-Negative Breast Cancer PSI Conference 2018, Amsterdam, The Netherlands, 3rd-6th June 2018 | Martina Sundqvist, Leanne de Koning, Guillem Rigaill, Thierry Dubois, Julien Chiquet |
| 2017 | Presentation: Therapeutic Rationale to Target Highly Expressed CDK7 Conferring Poor Outcomes in Triple-Negative Breast Cancer European Alliance for Personalised Medicine Congress, Belfast, UK, 27-30th November 2017 | Bo Li |
| 2017 | Presentation: MammaPrint on an NGS platform: Decentralised performance in your lab / MammaPrint: Personalising care for patients with early-stage breast cancer COMBAT for Breast Cancer, Dusseldorf, Germany, 14th October 2017 | Annuska Glas |
| 2017 | Presentation: American Association for Cancer Research (AACR) Annual Meeting 29th European Congress of Pathology, Amsterdam, The Netherlands, 5th September 2017 | Annuska Glas |
| 2017 | Poster: MammaPrint 70 gene test using RNA sequencing technology American Association for Cancer Research (AACR) Annual Meeting, Washington, USA, 1st April 2017 | Lorenza Mittempergher |
| 2017 | High CDK7 is Linked to Poor Outcome in Triple-Negative Breast Cancer and is a Rational Therapeutic Target Irish Association for Cancer Research (IACR), Kilkenny, Ireland, 24th February 2017 |
Li B, Ni Chonghaile T, O’Connor D, Gallagher W et al. |
| 2016 | Phase II of POSEIDON: A phase Ib / randomized phase II trial of tamoxifen plus taselisib or placebo in hormone receptor positive, HER2 negative, metastatic breast cancer patients with prior exposure to endocrine treatment San Antonio Breast Cancer Symposium 2016, Texas, USA, 6-10th Dec 2016 |
Oliveira M (VHIO), Baird RD, van Rossum A, Beelen K, Garcia-Corbacho J, Mandjes I, Vallier AL, van Werkhoven E, Garrigós L, Kumar S, van Tinteren H, Muñoz S, Linossi C, Rosing H, Miquel JM, Schrier M, de Vries Schultink A, Saura C, Gallagher WM, Bernards R, Tabernero J, Cortés J, Caldas C and Linn S |
| 2016 | POSEIDON trial phase 1b results: Safety and preliminary efficacy of the isoform selective PI3K inhibitor taselisib (GDC0032) combined with tamoxifen in hormone receptor (HR) positive, HER2-negative metastatic breast cancer (MBC) patients (pts) including response monitoring by plasma circulating tumour (ct) DNA Poster, ASCO 2016, and selected for Poster Discussion session, Chicago, USA, 3-7th Jun 2016 |
Richard D. Baird (CAM), Annelot Van Rossum, Mafalda Oliveira, Karin Beelen, Javier GarciaCorbacho, Ingrid A M Mandjes, AnneLaure Vallier, Erik D. van Werkhoven, Sanjeev Srinivas Kumar, Harm van Tinteren, Emma Beddowes, Hilde Rosing, Mariette Schrier, Aurelia de Vries Schultink, Cristina Saura, Rene Bernards, Josep Tabernero, Javier Cortes, Carlos Caldas, Sabine C. Linn |
| 2016 | Master regulators of breast tumour progression: a source of robust prognostic biomarkers Talk, Clinical Decision Support Systems for Breast and Prostate Cancer, Dublin, Ireland, 7-8th Mar 2016 |
William Gallagher (UCD) |
| 2016 | Bromodomain Inhibitors for the Treatment of Invasive Lobular Carcinoma
Irish Association for Cancer Research Annual Conference Cork, Ireland, 24th – 26th February 2016 |
Louise Walsh (UCD), Finbarr Tarrant, Ye Fan, William M. Gallagher, Tríona Ní Chonghaile, Darran P. O’Connor |
| 2016 | Epigenetic Modulators for the Treatment of Invasive Lobular Carcinoma Breast Cancer Poster, International Cell Death Society Conference Cork, Ireland, 2nd – 4th June 2016 |
Louise Walsh (UCD), Finbarr Tarrant, Ye Fan, William M. Gallagher, Tríona Ní Chonghaile, Darran P. O’Connor |
| 2016 | Epigenetic Modulators for the Treatment of Invasive Lobular Carcinoma Breast Cancer Poster, European Association for Cancer Research conference series ‘A Matter of Life or Death’ Amsterdam, Netherlands, 9th – 11th May 2016 |
Louise Walsh (UCD), Finbarr Tarrant, William M. Gallagher, Tríona Ní Chonghaile, Darran P. O’Connor |
| 20 | Protein-based assays: how to position them in personalised medicine trials Talk, Molecular Analysis For Personalised Therapy (MAP) Conference, Paris, France, 23-24th Oct 2015 |
Leanne De Koning (IC) |
| 2015 | RPPA as a Tool to Identify New Biomarkers and Potential Therapeutic Targets for Invasive Lobular Breast Cancer Talk, Global RPPA Workshop, Virginia, USA, 12-13th Oct 2015 |
Leanne De Koning (IC) |
| 2015 | Epigenetic modulators for the treatment of Invasive Lobular Carcinoma Breast Cancer Talk, Royal Academy of Medicine Ireland, Dublin, Ireland |
Louise Walsh, T Ni Chonghaile, Y Fan, DP O’Connor, WM Gallagher |
| 2015 | Reverse Phase Protein Arrays as a tool to identify new biomarkers and potential therapeutic targets for breast cancer subtypes Talk, SELECTBIO Microarray Technology conference, Berlin, Germany, 17th-18th March 2015 |
Leanne De Koning |
| 2015 | CDK7: A marker of poor prognosis and tractable therapeutic target in triple-negative breast cancer Talk, Irish Association of Cancer Research Annual meeting, 26th-27th February 2015, Limerick, Ireland |
Bo Li, T Ni Chonghaile, Y Fan, R Kinger, AE O’Connor, DP O’Connor, WM Gallagher |
| 2015 | Epigenetic modulators for the treatment of Invasive Lobular Carcinoma Breast Cancer Poster, Irish Association of Cancer Research Annual meeting, 26th-27th February 2015, Limerick, Ireland |
Louise Walsh, T Ni Chonghaile, Y Fan, DP O’Connor, WM Gallagher |
| 2014 | New treatment strategy of invasive lobular carcinoma Poster, Cell Symposia: Hallmarks of Cancer: Asia. 9th November, 2014, Beijing, China |
Z. Xue, I. Majewski, M. Michaut, A. Bosma, P. Halonen, L. Wessels, R. Bernards |
| 2014 | Deciphering protein signaling networks in lobular breast cancer samples Seminar, Institut Curie, Paris, France, 7th Oct 2014 |
Leanne De Koning |
| 2014 | RATHER: High Resolution Molecular Profiling of Lobular and Triple Negative Breast Cancers Poster, Beyond Genome Boston, USA, 8th-10th October 2014 |
Suet-Feung Chin, Oscar Rueda, Bernard Pereira, Ian Majewski, Yue Fan, Finbarr Tarrant, Magali Michaut, Justine Peeters, Philip Schouten, Leanne de Koning, Beilei He, Sarah McGuire, Helen Bardwell, Elena Provenzano, Darran P. O’Connor, Jeroen Heijmans, Mireille Snel, Tesa Severson, Astrid Bosma, Lorenza Mittempergher, Tycho Bismeijer, Sabine Linn, Thierry Dubois, Lodewyk Wessels, Iris Simon, William M. Gallagher, René Bernards, Carlos Caldas |
| 2014 | Epigenetic modulators for the treatment of Invasive Lobular Carcinoma Breast Cancer Poster, Conway Festival, University College Dublin. 10th September 2014 |
Louise Walsh, T Ni Chonghaile, Y Fan, DP O’Connor, WM Gallagher |
| 2014 | Reverse phase protein array profiling of Lobular and Triple Negative Breast Cancers within the RATHER consortium Poster, EACR Annual Meeting 2014, 5th-8th July, Munich, Germany |
Leanne de Koning, Beilei He, Aurélie Barbet, Floriane Bard, Caroline Lecerf, Céline Baldeyron, Thierry Dubois |
| 2014 | RATHER: high resolution molecular profiling of lobular and triple negative breast cancers Poster, EACR Annual Meeting 2014, 5th-8th July, Munich, Germany |
Suet-Feung Chin, Oscar Rueda, Bernard Pereira, Ian Majewski, Yue Fan, Finbarr Tarrant, Magali Michaut, Justine Peeters, Philip Schouten, Leanne de Koning, Beilei He, Sarah McGuire, Helen Bardwell, Elena Provenzano, Darran P. O’Connor, Jeroen Heijmans, Mireille Snel, Tesa Severson, Astrid Bosma, Lorenza Mittempergher, Tycho Bismeijer, Sabine Linn, Thierry Dubois, Lodewyk Wessels, Iris Simon, William M. Gallagher, René Bernards, Carlos Caldas |
| 2014 | Development of a BRCA1-like signature in triple negative breast cancers within the RATHER (Rational Therapy for Breast Cancer) Consortium Poster, IMPAKT 2014 Breast Cancer Conference, Brussels, Belgium, 8th-10th May 2014 |
I. Simon, J. Peeters, T. Severson, I. Majewski, A. Bosma, S-F. Chin, C. Caldas, R. Bernards, S. Linn |
| 2014 | Identification of novel kinase targets in triple-negative breast cancer Poster, Irish Association of Cancer Research Annual Meeting, 27th-28th February 2014, Galway, Ireland |
Bo Li, Yue Fan, Aisling O’Connor, Rut Klinger, Kate Connor, Darran O’Connor, and William M. Gallagher |
| 2013 | Identification of novel kinase targets in triple-negative breast cancer Poster, Conway Festival, University College Dublin |
Bo Li, Yue Fan, Aisling O’Connor, Rut Klinger, Kate Connor, Darran O’Connor, and William M. Gallagher |
| 2013 | Defining clinically relevant molecular subtypes in lobular breast cancer within the RATHER Consortium Poster, San Antonio Breast Cancer Symposium 2013, USA |
Sabine Linn, Ian Majewski, Magali Michaut, Justine Peeters, Philip Schouten, Leanne de Koning, Beilei He, Yue Fan, Finbarr Tarrant, Darran P. O’Connor, Oscar Rueda, Suet-Feung Chin, Jeroen Heijmans, Mireille Snel, Tesa Severson, Astrid Bosma, Lorenza Mittempergher, Tycho Bismeijer, Thierry Dubois, Lodewyk Wessels, Iris Simon, William M. Gallagher, Carlos Caldas, René Bernards |
| 2013 | RATHER: High Resolution Molecular Profiling of Lobular and Triple Negative Breast Cancers Poster, AACR Advances in Breast Cancer, 3rd -6th October 2013, San Diego, USA |
Suet-Feung Chin, Oscar Rueda, Bernard Pereira, Ian Majewski, Yue Fan, Finbarr Tarrant, Magali Michaut, Justine Peeters, Philip Schouten, Leanne de Koning, Beilei He, Sarah McGuire, Helen Bardwell, Elena Provenzano, Darran P. O’Connor, Jeroen Heijmans, Mireille Snel, Tesa Severson, Astrid Bosma, Lorenza Mittempergher, Tycho Bismeijer, Sabine Linn, Thierry Dubois, Lodewyk Wessels, Iris Simon, William M. Gallagher, René Bernards, Carlos Caldas |
| 2013 | Identification of novel kinase targets in triple-negative breast cancer Poster, Conway Festival, 11th-12th September 2013, University College Dublin, Ireland |
Bo Li, Yue Fan, Aisling O’Connor, Rut Klinger, Kate Connor, Darran O’Connor, and William M. Gallagher |
| 2013 | Revealing Kinase Deregulation in Lobular Breast Cancer via High-Throughput Molecular Profiling Within the RATHER Consortium Poster, The Genomics of Common Diseases Conference 2013, Oxford, UK |
Yue Fan, Finbarr Tarrant, Ian Majewski, Magali Michaut, Justine Peeters, Philip Schouten, Leanne de Koning, Beilei He, Darran P. O’Connor, Oscar Rueda, Suet-Feung Chin, Jeroen Heijmans, Mireille Snel, Tesa Severson, Astrid Bosma, Lorenza Mittempergher, Tycho Bismeijer, Sabine Linn, Thierry Dubois, Lodewyk Wessels, Iris Simon, William M. Gallagher, Carlos Caldas, René Bernards |
| 2013 | Investigation of BRCA1-like signature in triple negative breast cancers within the RATHER (Rational Therapy for Breast Cancer) Consortium Poster, AACR Annual Meeting 2013, Washington DC, USA |
Tesa Severson, Justine Peeters, Ian Majewski, Astrid Bosma, Suet-Feung Chin, Carlos Caldas, Iris Simon, René Bernards, Sabine Linn |
| 2013 | DNA repair genes and BRCA1-like classification in the RATHER triple negative breast cancers Poster, Breakthrough Breast Cancer Triple Negative Breast Cancer Conference 2013, London, UK, 26th-28th June, 2013 |
Tesa Severson, Justine Peeters, Ian Majewski, Magali Michaut, Philip Schouten, Astrid Bosma, Suet-Feung Chin, Carlos Caldas, Iris Simon, Lodewyk Wessels, René Bernards, Sabine Linn |
| 2013 | Development of comprehensive molecular portraits of lobular breast cancer within the RATHER (Rational Therapy for Breast Cancer) Consortium Poster, AACR Annual Meeting 2013, Washington DC, USA |
Justine Peeters, Ian Majewski, Leanne de Koning, Yue Fan, Finbarr Tarrant, Darran O. O’Connor, Jeroen Heijmans, Mireille Snel, Tesa Severson, Astrid Bosma, Magali Michaut, Lorenza Mittempergher, Beilei HE, Thierry Dubois, William M. Gallagher, Carlos Caldas, René Bernards, Iris Simon |
| 2013 | Development of comprehensive molecular portraits of lobular breast cancer within the RATHER (Rational Therapy for Breast Cancer) Consortium Talk, IACR Annual Meeting 2013, Dublin, Ireland |
Yue Fan, Finbarr Tarrant, Darran P. O’Connor, Ian Majewski, Justine Peeters, Leanne de Koning, Kate Connor, Jeroen Heijmans, Mireille Snel, Tesa Severson, Astrid Bootsma, Magali Michaut, Lorenza Mittempergher, Thierry Dubois, Iris Simon, Carlos Caldas, René Bernards, William M. Gallagher |
| 2012 | Kinome capture sequencing to discover new signalling pathways that contribute to cancer pathogenesis Poster, 24th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics, Dublin |
Ian Majewski, Zheng Xue, Lorenza Mittempergher, Magali Michaut, Roel Kluin, Astrid Bosma, Justine Peeters, Leanne de Koning, Thierry Dubois, Lodewyk Wessels and René Bernards |
| Invited Talks | ||
|---|---|---|
| 2016 | A Vulnerability of Drug Resistant Melanomas With Therapeutic Implications Symposia on Cancer Research 2016 – Cancer evolution: the mechanisms of vulnerability and resistance; MD Anderson Cancer Centre, Texas, USA, 6th Oct 2016 |
René Bernards (NKI) |
| 2016 | Molecular heterogeneity in ILC Talk, 1st International Invasive Lobular Cancer Symposium, Pittsburgh, USA, 29-30th Sept 2016 |
Suet-Feung Chin (CAM) |
| 2015 | Translation of omic data into personalised oncology tools: the challenge and the reward Select Biosciences Online Conference – Diagnostics & Biomarkers, 27 – 28 January 2015 |
William Gallagher |
| 2014 | Fast-tracking molecular diagnostics in oncology via antibody-based proteomics and digital pathology Royal College of Surgeons in Ireland/Beaumont Hospital, Dublin, 23 April 2014 |
William Gallagher |
| 2014 | Development of a campus spinout: one foot in academia and the other in industry Irish Association for Cancer Research, Galway, 27-28 February 2014 |
William Gallagher |
| 2014 | Fast-tracking molecular diagnostics in oncology via antibody-based proteomics and digital pathology University of Torino, Torino, 3 February 2014 |
William Gallagher |
| 2013 | Towards precision medicine in oncology: The advent of molecular diagnostics Association of Clinical Biochemists in Ireland (36th Annual Conference), Dublin, 18 – 19 October 2013 |
William Gallagher |
| 2013 | Getting EU funding: The experience of the RATHER project Horizon 2020 Health Information Day, European Commission, Centre Albert Borschette, Brussels, 22 November 2013 |
William Gallagher |
| 2013 | Tackling the validation bottleneck: Fast-tracking molecular diagnostics in oncology via antibody-based proteomics and digital pathology Bioconference Live 2013, Cancer: Research, Discovery and Therapeutics, 16 – 17 October 2013 |
William Gallagher |
| 2013 | Fast-tracking molecular diagnostics in oncology via antibody-based proteomics and digital pathology Molecular Medicine Congress 2013: Biomarkers and Applications of Exosomes Track, Frankfurt, 3 – 4 September 2013 |
William Gallagher |
| 2013 | Development of a campus spinout: one foot in academia and the other in industry Irish Association for Cancer Research, Maynooth, 14 May 2013 |
William Gallagher |
| 2013 | Industry-academic partnerships in the oncology molecular diagnostics sector Life Sciences Summit, Dublin, 1 March 2013 |
William Gallagher |
| 2013 | Translational perspectives in cancer biology: case studies in biomarker and drug development University College Cork Seminar Series, 12 February 2013 |
William Gallagher |
| 2013 | Advice from a “successful” FP7 co-ordinator FP7 Health Co-Ordinators Support Workshop, Dublin, 9 January 2013 |
William Gallagher |
| 2012 | Fast-tracking molecular diagnostics in oncology via antibody-based proteomics and digital pathology KU Leuven, Leuven, 11 December 2012 |
William Gallagher |
| 2012 | Fast-tracking molecular diagnostics in oncology via antibody-based proteomics and digital pathology Cancer Proteomics 2012, Madrid, 16 – 17 October 2012 |
William Gallagher |
| 2012 | Aiding biomarker development through effective industry-academia partnerships 3rd Annual External & Collaborative Innovation in Life Science R&D;, London, 3 October 2012 |
William Gallagher |
| 2012 | All-board the brain train! Experiences of Europe’s global scientific diaspora Wild Geese Careers Forum, EuroScience Open Forum 2012, Dublin, 11 – 15 July 2012 |
William Gallagher |
| 2012 | Fast-tracking molecular diagnostics in oncology via antibody-based proteomics and digital pathology Next Generation Molecular Diagnostics, Prague, 12 – 13 June 2012 |
William Gallagher |
| 2012 | OncoMark: case study presentation Collaborate to Innovate (European Research & Innovation Funding for SMEs), Belfast, 7 June 2012 |
William Gallagher |
| 2012 | OncoMark: a case study in innovation within the life sciences sector Ireland’s Presidential Priorities: Jobs and Innovation, Dublin, 22 May 2012 |
William Gallagher |
| 2012 | Fast-tracking molecular diagnostics in oncology via antibody-based proteomics and digital pathology Molecular Diagnostics Europe 2012 (Disease Biomarkers Track), London, 10 – 11 May 2012 |
William Gallagher |
| 2012 | Towards tailored treatment for triple negative breast cancer and invasive lobular carcinoma of the breast: a kinase-centric viewpoint (RATHER) AACR Annual Meeting 2012, Chicago |
René Bernards |
| 2012 | Fast-tracking molecular diagnostics in oncology via antibody-based proteomics and digital pathology Genomics Research 2012 (Genomic Biomarkers Track), Boston, 19 – 20 April 2012 |
William Gallagher |
| 2012 | Fast-tracking molecular diagnostics in oncology via antibody-based proteomics and digital pathology Advances in Microarray Technology 2012, Edinburgh, 28 – 29 March 2012 |
William Gallagher |
| 2012 | OncoMark: A case study of innovation European Universities Centre Symposium 2012, Dublin, 12 March 2012 |
William Gallagher |
| 2012 | Case study presentation – EU projects in the cancer arena UCD Focus on Industry-Academia Partnership and Pathways Programme, Dublin, 14 February 2012 |
William Gallagher |
| 2012 | Aiding biomarker development through effective industry-academia partnerships Biomarkers Summit 2012, London, 16 – 17 January 2012 |
William Gallagher |
| 2012 | Fast-tracking molecular diagnostics in oncology via antibody-based proteomics and digital pathology Centre for Systems Medicine, Royal College of Surgeons in Ireland, Dublin, 11 January 2012 |
William Gallagher |
| 2011 | Antibody-based proteomics: fast-tracking molecular diagnostics in oncology International Conference on ‘Omics Meets Disease’ and 3rd Annual Meeting of Proteomics Society (India), Kolkata, 15 – 18 December 2011 |
William Gallagher |
| 2011 | Antibody-based proteomics: fast-tracking molecular diagnostics in oncology iSymposia Online Conference ‘Mining for Cancer Biomarkers: From Genes to Tissues’, 13 – 15 December 2011 |
William Gallagher |
| 2011 | Case study presentation – EU projects in the cancer arena InterTradeIreland – Focus on FP7 Series – Cancer Research. Dublin, 17 November 2011 |
William Gallagher |
| 2011 | Workshop on European Framework Programme SFI Science Summit 2011 (Shaping the Future Now – New Horizons for Science and Society), Athlone, 14 – 15 November 2011 |
William Gallagher |
| 2011 | Fast-tracking molecular diagnostics in oncology via antibody-based proteomics and digital pathology BioConference Live Fall: Life Sciences, 26-27 October 2011 [see Archived presentation on www.bioconferencelive.com] |
William Gallagher |
| 2011 | Antibody-based proteomics: translating omic datasets into clinically relevant assays Microarray World Congress, San Francisco, 29 – 30 September 2011 |
William Gallagher |
| 2011 | Translational perspectives in cancer biology: case studies in biomarker and drug development 11th Annual Conway Festival of Research and Innovation, Dublin, 15 September 2011 *Plenary Speaker |
William Gallagher |
| 2011 | Antibody-based proteomics: translating omic datasets into clinically relevant assays Beckman Coulter 2011 Science & Technology Symposium “Cancer Diagnostics – Confronting the Complexity”, Brea, CA, 6 – 7 July 2011 |
William Gallagher |
| 2011 | Bridging the translational divide: converting omic datasets into clinically relevant assays Advances in Microarray Technology 2011 (part of European Lab Automation conference), Hamburg, 30 June – 1 July 2011 |
William Gallagher |
| 2011 | Bridging the translational divide: converting omic datasets into clinically relevant assays EMBO Cancer Proteomics 2011, Dublin, 20 – 23 June 2011 |
William Gallagher |
| 2011 | Translational persectives in cancer biology: case studies in biomarker and drug development Institute of Molecular Medicine Lecture Series, Dublin, 23 May 2011 |
William Gallagher |
| 2011 | A systematic investigation of tumour biomarkers: taking advantage of the digital pathology framework European Biomarkers Summit 2011, London, 18 – 19 May 2011 *Keynote seminar |
William Gallagher |
| 2011 | Proteomics in the discovery of circulating biomarkers in cancer. Educational Session on “Clinical Use of Circulating Biomarkers: The Good, The Bad and the Ugly” 102nd Annual Conference of the American Association for Cancer Research, Orlando Florida, 2 – 6 April 2011 |
William Gallagher |
| 2011 | Tissue-based imaging: automated image analysis approaches in histopathology Quantitative Biology and Bioinformatics in Modern Medicine – International Conference, University College Dublin, 7 – 8 February 2011 |
William Gallagher |
| Dissemination to Lay Persons | ||
|---|---|---|
| 2016 | Breast Cancer – the answer is in Epigenetics? Thesis in 3, Royal College of Surgeons, Ireland, 2016 |
Louise Walsh (UCD), Finbarr Tarrant, Ye Fan, William M. Gallagher, Tríona Ní Chonghaile, Darran P. O’Connor |
| 2015 | Discussing RATHER and the POSEIDON clinical trial CRCfm (local Irish radio station), Oct 2015 |
Karen Misstear (OM) |
| 2015 | Targeting the drivers of difficult-to-treat breast cancers |
European Commission Horizon 2020 article about the RATHER project and clinical trial, for World Cancer Day – 4th Feb 2015 |
| 2014 | EU breast cancer research targets personalised treatment |
European Commission press release, 27th Oct 2014, referencing RATHER as a promising breast cancer research programme |
| 2014 | Cancer knows no boundaries- but we can slow death rate Newspaper article in the Irish Independent newspaper for World Cancer Day |
Marie Geoghegan Quinn, the EU Commissioner for Research, Innovation and Science. Referencing the Irish RATHER partners UCD and OM. |
| 2014 | Laura van’t Veer was rewarded 2nd prize as best EU Women Innovator 2014 |
AG |
| 2013 | Getting EU funding: The Experience of the RATHER project |
Horizon 2020 Health Information Day, European Commission, Brussels, 22 November 2013 |
| 2012 | The True Cost of Personalised Cancer Medicine EuroScience Open Forum (ESOF12) 2012 |
William M Gallagher, Iris Simon |
| 2012 | iInterview by Dr. Alberto Cambrosio Focus on universities and innovative spinout companies. Department of Social Studies of Medicine McGill University, Montreal Mon 23 Apr 2012 |
William M Gallagher, Máirín Rafferty, René Bernards, Iris Simon |
| 2011-2015 | Various press releases |
UCD, OM, AG, EC |
